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KMID : 0357919760100020203
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Korean Journal of Pathology
1976 Volume.10 No. 2 p.203 ~ p.210
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Study on Serum Alpha-Fetoprotein and Hepatitis-associated Antigen in Patients with Primary Hepatoma
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이영헌(李榮憲)/Yung Heon Lee
김재식(金在植)/김중명(金重明)/Jae Sik Kim/Jyung Myung Kim
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Abstract
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Alpha-fetoprotein (AFP) and hepatitis-associated antigen (HAA) have been checked by
the method of agarose gel immunodiffusion with 303 Korean patients including 79
patients of primary hepatoma, 169 patients of miscellaneous liver diseases, 25 cases of
extrahepatic malignant tumor, and 30 normal persons for the recent two years from July
1974 to June 1976 and the results are as follows.
1. AFP was positive in 46 of 79 cases (58.2%) with primary hepatoma, 2 of 92 cases
with liver cirrhosis, and 1 of two neonatal hepatitis.
2. The occurrence of HAA in patients with primary hepatoma is 18 of 76 cases (23.6%)
3. AFP positive cases in hepatomas showed positive HAA in 15 of 51 (29.1%) and AFP
negative cases showed 3 of 25 (12.0%) respectively. The frequency of HAA positive
in hepatomas seemed to be higher in AFP positive cases than AFP negative.
4. The primary hematoma showed a tendency of higher incidence of AFP positivity in
young age group than elderly persons.
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KEYWORD
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